Negative Space tells the story of a provocative Los Angeles painter named Max Higgins, on the verge of local fame. The secret to his work's haunting allure? He collects photos of missing persons and incorporates them into his paintings, giving the often melancholy faces, as he puts it, a "home in his work." This fascination stems from the bizarre disappearances of people he knew growing up, including his father. Then, one day, someone recognizes a face in one of his paintings, and he is suddenly thrust into a journey as surreal as anything from his brush, a journey into his past that will determine irrevocably his future.